Image of 96-well, 100ul volume plate setup

Need to run a dialysis experiment for many small volume samples in parallel?

Pierce Microdialysis Plates offer a ready-to-use disposable dialysis solution designed for multiplexing of up to 96 x 0.1–0.3 mL samples (or 48 x 0.3–1.0 mL samples) in parallel with a variety of MWCOs for your small volume dialysis needs. The devices feature regenerated cellulose membranes with very large surface-area-to-volume ratio for dialysis experiments in 2–4 hours.

Features of Pierce Microdialysis Plates include:

  • High yield—greater than 90% protein recovery after dialysis
  • Rapid—dialysis completed in 2–4 hours
  • Easy to use—sample loading and retrieval can be done with a standard pipette tip
  • Flexible—detachable 6-device strips, scalable from 1 to 48 samples
  • Automation compatible—plate format conforms to the SBS Microplate Standard and can be used with automated liquid handling systems

Pierce Microdialysis Plates are commonly used for a variety of protein sample cleanup purposes including:

  • Protein and DNA desalting/buffer exchange
  • Small molecule contaminate and unused reagent removal
  • Removal of dyes after protein labeling
Image depicting a variety of volumes and MWCO’s of the Slide-A-Lyzer G3

Need to dialyze a larger volume sample?

Try Thermo Scientific Slide-A-Lyzer G3 Cassettes or Slide-A-Lyzer Dialysis Flasks for volumes from 1 mL to 250 mL. Slide-A-Lyzer dialysis cassettes and flasks offer a user-friendly approach to traditional dialysis tubing by incorporating dialysis membranes into a rigid frame with a secure cap which allows for easier sample loading/retrieval and increased sample security.

Find out more

Select your microdialysis device

 Image of 96-well, 100ul volume plate setupImage of 96-well, 300ul volume plate setupImage of 48-well, 1ml volume plate setup
 

Max Volume

MWCO

0.1 mL

0.3 mL

1 mL

2k

A50462
(96-well)

A50465
(96-well)

A50466
(48-well)

3.5k

88262
(96-well)

A50467
(96-well)

A50468
(48-well)

10k

88260
(96-well)

A50469
(96-well)

A50470
(48-well)

20k

A50471
(96-well)

A50472
(96-well)

A50473
(48-well)

Cat. No. 88261 - 96-well Deep-well Plate, 2.2 mL, for Pierce 96-well Microdialysis

Required for use with 96-well microdialysis devices, the Thermo Scientific Pierce 96-well Deep-well Plate, 2.2 mL, is a polypropylene deep-well assay plate sufficient for 96 microdialysis devices. For 48-well microdialysis kits the deep-well plate is provided by default.

Cat. No. 88269 - Plate Seal for Pierce 96-well Microdialysis Plates

Adhesive-coated plastic sheets to seal 96-well or 48-well microdialysis plates to protect against contamination and evaporation, suitable for long-term storage.

Reference figures
RED Device with Plate

Want to do dialysis for drug-binding studies?

The RED (Rapid Equilibrium Dialysis) and Competition RED systems utilize a disposable device format that is automation-friendly, providing convenience for scientists conducting plasma or tissue-to-plasma and protein-binding studies.

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Resources

Dialysis Product Selection Guide
Pierce Protein Concentrators
Zeba Desalting Products

Learning resources

Protein Biology Learning Center
Protein Isolation and Purification Learning Center
Dialysis Methods for Protein Research

For Research Use Only. Not for use in diagnostic procedures.