Experimental Design & Assay Development

Design the right assay for your screen with a broad range of tools for assay development

Whether you’re performing a functional genomics screen in a widely used cell line or difficult-to-transfect primary cell type, Thermo Fisher Scientific offers advanced tools for experimental design and assay development. Our comprehensive portfolio includes RNAi products and gene-editing solutions such as the CRISPR-Cas9 system, industry-leading transfection reagents, trusted cell culture solutions, effective gene- and cell-based assays, and a broad range of endpoint analysis instruments from high-content imaging to reporter assay systems. These products can help you get started on the right path to discovery in your gene function studies. We can also assist with assay and protocol development to simplify the process and accelerate your work.

functional genomics screening workflow

Assay development:

siRNA libraries

Predefined and custom sets of premium-quality Invitrogen™ Silencer™ and Silencer™ Select siRNA Libraries, for performing RNAi experiments in human, mouse, and rat cell systems (minimum order of 20 siRNAs for a custom library)

miRNA libraries

  • 100% coverage of miRBase Sequence Database Version 20 
  • All distinct individual miRNA mimics and inhibitors covered, and available typically with fast turnaround
  • Available as whole human, mouse, and rat libraries or smaller custom libraries (minimum order of 20 miRNAs for a custom library)
  • Practical 96-well or 384-well plate format for high-throughput screening, with complete plate layout information

CRISPR libraries 

CRISPR libraries are emerging as the next-generation tool for high-throughput functional genomics screening. Thermo Fisher Scientific introduces arrayed CRISPR libraries for screening applications.

Cell culture

From basic formulations to the newest innovations, Gibco™ products provide the highest quality, consistency, and performance for your cell culture and tissue culture needs, including cell culture media, reagents, cell lines, cell cultures, cell culture bags, fetal bovine serum, and growth factors for your research and bioproduction needs.

Transfection

Expertise in cellular and molecular biology is behind the Invitrogen™ product portfolio of DNA reagents and consumables, which include the most-cited and trusted transfection and selection systems available. Choose from our broad range of transfection technologies, including lipid transfection and chemical and physical methods such as electroporation.

To learn more about what Thermo Fisher Scientific has to offer for your functional genomics screening workflow, select from our Primary & Validation Screening and In Vitro & In Vivo Studies

For Research Use Only. Not for use in diagnostic procedures.