Ambion In Vivo siRNA molecules are chemically modified, 21-mer, double-stranded siRNAs that are recognized by the RNA-induced silencing complex (RISC) to mediate inhibition of a target gene. Proprietary chemical modifications allow Ambion In Vivo siRNAs to overcome many in vivo–specific obstacles, ensuring their effectiveness and stability in vivo. Ambion In Vivo siRNAs are at least 100x more stable in 90% mouse serum than unmodified siRNAs.
Ambion In Vivo siRNAs, the new standard for in vivo RNAi applications, offer:
- High stability against nucleases
- No induction of the interferon response
- Easy tracking of administered siRNAs
- Combined knockdown effectiveness and stability
|4457298||Standard Purity||5 nmol|
|4457302||HPLC purified||250 nmol|
|4457304||HPLC purified||1 umol|
|4457306||HPLC purified||10 umol|
|4457308||HPLC In Vivo Ready||250 nmol|
|4457310||HPLC In Vivo Ready||1 umol|
|4457312||HPLC In Vivo Ready||10 umol|
For Research Use Only. Not for use in diagnostic procedures.