RNAi Lab Essentials

RNAi solutions for efficient and specific gene silencing

RNAi is a powerful, effective, and well-characterized method for gene silencing for loss-of-function studies. This technology is proven in elucidation of biological pathways, disease gene analysis, and target gene discovery.

At Thermo Fisher Scientific, we have developed a broad suite of tools for RNAi applications, including short interfering RNA (siRNA) for targeted gene knockdown and microRNA (miRNA) reagents to mimic or inhibit endogenous gene regulators. These market-leading reagents are suitable for in vivo or in vitro research, including high-throughput screening with RNAi libraries. Learn more about how we can help with end-to-end solutions for the entire RNAi workflow.

Download RNAi handbook

 siRNA

RNAi using siRNA is a superior way to effectively knock down gene expression to study protein function in a wide range of cell types.

 miRNA

Functional analysis of regulatory RNAs such as miRNA can help decipher complex cellular processes in development and disease etiology.

 RNAi Controls

We offer a selection of positive and negative controls to help ensure that researchers are able to carry out reproducible, high-quality gene silencing experiments.

Discover tools to support the RNAi workflow

RNAi Workflow Step 1: Select

Choose an RNAi reagent for your target gene

RNAi Workflow Step 2: Deliver

Efficiently transfect your RNAi reagent

RNAi Workflow Step 3: Verify
RNAi Workflow Step 4: Analyze

Determine loss-of-function effects

RNAi Workflow Step 1: Select

Choose an RNAi reagent for your target gene

RNAi Workflow Step 2: Deliver

Efficiently transfect your RNAi reagent

RNAi Workflow Step 3: Verify
RNAi Workflow Step 4: Analyze

Determine loss-of-function effects


For Research Use Only. Not for use in diagnostic procedures.