Sanger sequencing instruments & accessories
Our Applied Biosystems genetic analysis systems are trusted for Sanger sequencing and fragment analysis, and proven through decades of results. Our Applied Biosystems genetic analysis systems can help you obtain excellent performance, reliability, and world-class support.
Which genetic analyzer is right for you?
| Easy to use, flexible system | Meets the needs of validated and process controlled environments | Maximum throughput and scalability | |
|---|---|---|---|
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| SeqStudio Genetic Analyzer | 3500 Series Genetic Analyzer | 3730 Series Genetic Analyzer | |
| Request a quote | Request a quote | Request a quote | |
| Number of capillaries | 4 | 8 (3500), 24 (3500xL) | 48 (3730), 96 (3730xl) |
| Ease of use | Simple | Easy | Moderate |
| Number of dyes | 6 | 6 | 5 |
| Capillary array length (cm) | Integrated into click-in cartridge | 36, 50 | 36, 50 |
| RFID | Yes | Yes | No |
| Polymer type | Integrated into click-in cartridge | POP-6, POP-7, POP-4 | POP-6, POP-7 |
| Sample capacity | 12 standard 8-strip tubes |
2 sample plates (96- or 384-well) | 16 sample plates (96- or 384- well) |
| Integrated plate stacker | No | No | Yes |
| Applications | Sequencing + fragment analysis on same run | Sequencing, fragment analysis | Sequencing, fragment analysis |
| Minimum run time | 30 min | 30 min | 20 min |
| Sequencing read length (bp) | 800 | At least 850 | 900 |
| Maximum sequencing throughput (base pair reads/day) | 67k | 138k (3500), 403k |
1.38 M (3730), 2.76 M |
| Maximum fragment throughput (samples/day)** | 192 | 384 (3500), 1,152 (3500xL) |
3,456 (3730), 6,912 (3730xl) |
| Learn more | Learn more | Learn more |
** Based on 20-plex microsatellites per well with optimal polymer, capillary, and run module combination
We provide a wide range of high-quality, end-to-end solutions to meet your Sanger sequencing and fragment analysis needs. We know that your results matter and are committed to manufacturing under strict quality-control standards and providing award-winning service to help you receive credible and accurate results—from sequencing reaction, to purification, capillary electrophoresis, and analysis.
Applied Biosystems genetic analyzers have enabled sequencing success for over 25 years.
We have you covered with sequencing and fragment analysis reagents for every application.
Applied Biosystems genetic analyzers support the widest range of applications for sequencing and fragment analysis.
View publications
 SeqStudio |
 3730xL |
 3730 |
 3500xL |
 3500 |
 3130xL |
 3130 |
 310 |
|
| Instrument | ||||||||
|---|---|---|---|---|---|---|---|---|
| Number of Capillaries | 96 | 48 | 24 | 8 | 16 | 4 | 1 | |
| Compatible applications: (S) Supported; (A) AB demonstrated; (C) Customer demonstrated; (N) Not supported |
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| BAC end sequencing | S | S | S | S | S | S | S | |
| Checking clone constructs | S | S | S | S | S | S | S | S |
| De novo sequencing | S | S | S | S | S | S | S | S |
| Heterozygote detection & resequenicng (SNP-based) | S | S | S | S | S | S | S | A |
| HLA typing | S | S | S | S | S | S | C | |
| Methylation | S | S | S | S | S | S | C | |
| mtDNA sequencing | S | S | S | S | S | S | S | S |
| Resequencing | ||||||||
| - Comparative genomics | S | S | S | S | S | S | S | S |
| - Indels | S | S | S | S | S | S | S | S |
| SAGE method | N | C | C | C | C | C | C | A |
| SNP analysis | S | S | S | S | S | S | S | S |
| General sizing of PCR products | S | S | S | S | S | S | S | S |
| Fragment length polymorphism | ||||||||
| - AFLP | N | S | S | S | S | S | S | S |
| - RFLP | N | A | A | A | A | A | A | A |
| Large fragment analysis | ||||||||
| - BAC fingerprinting | N | A | A | A | A | A | A | N |
| - VNTR | C | C | C | C | C | C | C | C |
| Microsatellite | ||||||||
| - Genotyping | S | S | S | S | S | S | S | S |
| - Analysis for forensics/HID | S | N | N | S | S | S | S | S |
| - Instability/RER | A | A | A | A | A | A | A | A |
| Conformation analysis | ||||||||
| - SSCP | N | N | N | N | N | A | A | S |
| Relative fluorescent quantitation | ||||||||
| - Loss of heterozygosity (LOH) | S (MLPA) | S | S | S | S | S | S | S |
| SNP genotyping | ||||||||
| - SNaPshot system | S | A | A | S | S | S | S | S |
| - SNPlex system | N | S | S | S | S | S | N | N |
| DNA protein binding assays & DNA fingerprinting | N | C | C | C | C | C | C | C |
Resources
- Sanger sequencing guide
- Sanger sequencing applications
- Fragment analysis guide
- Fragment analysis applications
- Sanger sequencing and fragment analysis software
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