Sanger Sequencing

Choose the genetic analyzer that is right
for you

Applied Biosystems genetic analyzers are a trusted standard for Sanger sequencing and fragment analysis by capillary electrophoresis (CE). Versatile and innovative, our genetic analyzers have been designed with you in mind to meet the demands of your genetic testing needs. Whether you're analyzing a challenging or a routine sample, our genetic analyzers offer simplicity, scalability, and speed to your workflow, enabling you to analyze your most difficult cases with complete confidence.

Which genetic analyzer is right for you?


Easy to use, versatile, and flexible

Meets the needs of validated and process-controlled environments

Maximum throughput, scalability, and flexibility

  SeqStudio Genetic Analyzer 3500 Series Genetic Analyzer Refreshed 3730 Series Genetic Analyzer
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Number of capillaries 4 8 (3500), 24 (3500xL) 48 (3730), 96 (3730xl)
Ease of use Simple Easy Moderate
Number of dyes 6 6 5
Capillary array length (cm) Integrated into click-in cartridge 36, 50 36, 50
RFID Yes Yes No
Polymer type POP-1 integrated into click-in cartridge POP-6, POP-7, POP-4* POP-6, POP-7
Sample capacity

12 standard 8-strip tubes
1 standard 96-well  plate 

2 sample plates (96- or 384-well) 16 sample plates (96- or 384- well)
Integrated plate stacker No No Yes
Applications Sequencing + fragment analysis on same run Sequencing, fragment analysis Sequencing, fragment analysis
Minimum run time 30 min 30 min 20 min
Sequencing read length (bp) 800 At least 850 900
Maximum sequencing throughput (base pair reads/day)  67k

138k (3500), 403k

1.38 M (3730), 2.76 M

Maximum fragment throughput (samples/day)**  192 384 (3500), 1,152
3,456 (3730), 6,912
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* POP-4 is generally only used with HID applications and requires GeneMapper ID-X Software for analysis.
** 96 capillaries are not recommended for fragment analysis.


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Get bite-sized answers to your everyday Sanger sequencing and fragment analysis questions

Learn about the history of sequencing and how to pick the right platform for your research needs