Induced Pluripotent Stem Cells (iPSCs)

The discovery in 2006 that human and mouse fibroblasts could be reprogrammed to generate induced pluripotent stem cells (iPSCs) with qualities remarkably similar to embryonic stem cells has created a valuable new source of pluripotent cells for drug discovery, cell therapy, and basic research.

Our stem cell research products have been an integral part of induced pluripotent stem cell research from the initial discovery of iPSCs to current breakthroughs. Our complete portfolio of stem cell research products and services provides optimized tools for each step of the stem cell workflow: from reprogramming somatic cells to iPSC expansion, validation, and differentiation.

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Cultured iPSCs following reprogramming

Reprogramming of somatic cells for iPSC generation can be accomplished by a number of technologies. We offer choices in integration-free reprogramming technologies and services that fit your research and translational needs including our Cell Therapy Systems (CTS) Products, which are designed for clinical and translational research applications.

Gibco iPSC culture products

iPSC research requires careful attention to culture conditions. From feeder-based and feeder-free media to optimized passaging reagents and substrates to media for stem cell therapy research, Gibco products enable you to culture with confidence.

Neon Transfection System for stem cell engineering

iPSCs are engineered to analyze disease pathways, better understand gene and protein expression, and study differentiation. Choose from Invitrogen gene editing and transfection technologies to build cell models that can better answer biological questions.

iPSCs differentiated for 14 days and stained for NKX2.5 (red) and TNNT2/cTNT (green) along with DAPI (blue)

iPSC differentiation requires standardized culture methods to ensure reproducible and reliable results. Gibco media, supplements, substrates, growth factors and cytokines provide you with an easy-to-use, flexible set of tools for targeted differentiation of induced pluripotent stem cells (iPSCs). Our differentiation portfolio allows optimal growth, expansion and storage of differentiated cells—enabling faster, more efficient systems.

Cultured iPSCs characterized with stem cell markers

iPSC characterization to validate cells and ensure they are pluripotent or have differentiated into the desired cell lineage is a critical step in your research. Our PluriTest compatible PrimeView Global Gene Expression Profile Assays provide rapid verification of pluripotency marker expression. The TaqMan hPSC Scorecard Panel is a quantitative method to confirm trilineage differentiation potential. Our KaryoStat and KaryoStat HD Assays provide whole-genome coverage for accurate detection of chromosomal abnormalities. These three assays provide a complete solution of tools to authenticate your iPSC lines with confidence.

Cultured iPSCs following reprogramming

Reprogramming of somatic cells for iPSC generation can be accomplished by a number of technologies. We offer choices in integration-free reprogramming technologies and services that fit your research and translational needs including our Cell Therapy Systems (CTS) Products, which are designed for clinical and translational research applications.

Gibco iPSC culture products

iPSC research requires careful attention to culture conditions. From feeder-based and feeder-free media to optimized passaging reagents and substrates to media for stem cell therapy research, Gibco products enable you to culture with confidence.

Neon Transfection System for stem cell engineering

iPSCs are engineered to analyze disease pathways, better understand gene and protein expression, and study differentiation. Choose from Invitrogen gene editing and transfection technologies to build cell models that can better answer biological questions.

iPSCs differentiated for 14 days and stained for NKX2.5 (red) and TNNT2/cTNT (green) along with DAPI (blue)

iPSC differentiation requires standardized culture methods to ensure reproducible and reliable results. Gibco media, supplements, substrates, growth factors and cytokines provide you with an easy-to-use, flexible set of tools for targeted differentiation of induced pluripotent stem cells (iPSCs). Our differentiation portfolio allows optimal growth, expansion and storage of differentiated cells—enabling faster, more efficient systems.

Cultured iPSCs characterized with stem cell markers

iPSC characterization to validate cells and ensure they are pluripotent or have differentiated into the desired cell lineage is a critical step in your research. Our PluriTest compatible PrimeView Global Gene Expression Profile Assays provide rapid verification of pluripotency marker expression. The TaqMan hPSC Scorecard Panel is a quantitative method to confirm trilineage differentiation potential. Our KaryoStat and KaryoStat HD Assays provide whole-genome coverage for accurate detection of chromosomal abnormalities. These three assays provide a complete solution of tools to authenticate your iPSC lines with confidence.