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Thermo Scientific Nunclon™ Sphera product line will make your most valuable work your best work. Learn more about how our newest cell culture and stem cell research products can meet your needs in the sections below.  

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Optimizing spheroid formation

Thermo Scientific Nunclon™ Sphera culture surface allows cells to grow in suspension with virtually no cell attachment. The new surface supports many different cell types and their ability to generate spheroids. Studies show that over time the spheroids grow in volume, indicating that the new surface enables consistent, repeatable cell growth.

Enhancing spheroid cultures across many cell types

Spheroid cultures

Expanding size of spheroids with different seeding density

Promoting formation of embryoid bodies (EB)

As an important milestone in the differentiation process, the Nunclon Sphera surface demonstrates superior quality for embryoid body formation of pluripotent stem cells with minimal spontaneous differentiation. The resultant cells are able to differentiate into all three germ layers.

Optimizing EB formation of Pluripotent stem cells

Optimizing EB formation

Outperforming other surfaces for consistent EB formation of different pluripotent stem cells

Outperforming other surfaces for consistent EB formation

Maintaining differentiation potential of pluripotent stem cells

Growing 3D cancer cultures

The Nunclon Sphera surface minimizes variability and supports the consistent formation of cancer spheroids that simulate the 3D structures of tumor growth, providing a better model system for studying tumor cell progression and efficacy of anticancer agents in vitro.

Outperforming non-treated Petri dish for cancer spheroid culture

Outperforming non-treated Petri dish

Generating favorable number of cancer spheroids

Generating favorable number of cancer spheroids