Thirty Years of Thermal Cycler 
Amazing scientific advancements have been made using Applied Biosystems thermal cyclers, from expanding our knowledge of human evolution, to sequencing human and many other genomes, to understanding genetic variation and drug efficacy in human disease research. We’ve been designing and manufacturing thermal cyclers since the first commercial thermal cycler, the TC1, in 1987. Over the decades we have continued to innovate, introducing many advances in block technology and intuitive graphical user interfaces. These innovations have made our customers’ research and scientific advancements possible—we’ve been honored to be part of your journey.

 Download 30 years of thermal cycler innovation timeline

Four decades of innovation

The 1980's

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The world’s 1st thermal cycler;
Taq DNA Polymerase revolutionized molecular biology.

The 1990's

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Paving the way for whole-genome sequencing and other amazing scientific discoveries.

The 2000's

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Increasing PCR throughput leads to advances in genomics research


Our ability to monitor and predict drug efficacy in living tissues is expanded.


Today’s thermal cyclers—which one is right for you?

Most flexible and highest throughput Elegant design, smart choice Proven reliability, precise PCR optimization Routine PCR, elevated Designed for easy robotic integration
ProFlex PCR System
Cloud enabled
SimpliAmp Thermal Cycler
Cloud enabled
Veriti Thermal Cycler** MiniAmp Thermal Cyclers
Cloud enabled
Automated Thermal Cycler (ATC)
**Also available as an FDA Class 1/ CE-IVD labeled device, click here for details

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Meet our innovators

Kenneth Tan
Sr. Product Manager

Keneth Tan

Kenneth has 20 years of experience in PCR-related products. He started his career as a project engineer responsible for thermal cycler technology transfer to manufacturing. He moved onto developing thermal cyclers as an R&D system engineer and then managed PCR and qPCR thermal cycler programs. Currently he is a thermal cycler and PCR plastics product manager. Kenneth holds seven patents related to Applied Biosystems VeriFlex temperature control technology, as well as to thermal cycler temperature uniformity.

Vincent Choo
Program Manager, Strategy & Portfolio Management

Vincent Choo

Vincent is a mechanical engineer and began working in thermal cycler design in 2001, focusing on thermal block module and enclosure design for the Applied Biosystems 9700 and Veriti Thermal Cyclers. He has since moved into program management, launching the ProFlex and SimpliAmp Thermal Cyclers in 2013, and the Automated Thermal Cycler in 2016.
Vincent holds two patents related to Applied Biosystems VeriFlex temperature control technology.

Bernard Boo
Sr. Manager, Engineering

Bernard Boo

Bernard is a systems engineer and began working in thermal cycler performance optimization in 2009. He then moved into leading mechanical design in 2014 and collaborated on the SimpliAmp Thermal Cycler design. Bernard holds two patents related to Applied Biosystems qPCR thermal cycler blocks, thermal control units and optical lenses.

CK Lim
Sr. Manager, Engineering

CK Lim

CK began working in thermal cycler design in 2002, focusing on thermal control optimization and architecture design for scalable thermal cycler implementation. CK holds eight patents related to Applied Biosystems VeriFlex temperature control technology, thermal cycler temperature uniformity, as well as Applied Biosystems qPCR thermal cycler blocks, thermal control units and optical lenses.

Learn more about our technology


PCR Solutions Brochure

Plastics compatibility chart for Applied Biosystems instruments

PCR and cDNA Synthesis Support Center 
Tips and troubleshooting help

School of Molecular Biology, PCR Education
Technical content for new and experienced molecular biologists

Thermal Cycler Software and Firmware Files
Download the latest updates for your instrument

Interested in private label thermal cyclers?
Submit an inquiry


We provide a full range of service options for all Applied Biosystems thermal cyclers.

Service plans

  • Rapid Exchange minimizes interruptions from unplanned instrument downtime
  • Global Repair Center provides a cost-efficient way to maximize uptime and achieve superior performance


Additional services available

Instrument qualification service: Have one of our engineers perform temperature qualifications at your site. You may also contact Instrument Services to purchase a temperature verification tool and perform the qualification yourself.