Our Newest Cellular Analysis Products and Technologies
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Click-IT® Edu Now Available in Larger Size
Click-iT® EdU offers a simplified method for detecting nascent DNA synthesis and is now available in a 5-gram size. EdU is an alkyne-containing nucleoside analog of thymidine whose detection is based on a click reaction, a copper (I)–catalyzed reaction between an azide and an alkyne. The small size of the detection azide allows the use of mild conditions to access EdU incorporated into DNA. The Click-iT® EdU assay can be completed in less than 90 minutes, without the need for immunoreagents or signal amplification.
Learn More about Click-iT® EdU
Comparison of signal strength in tissues labeled with EdU (A) or BrdU (B).
New Mitochondrial Antibodies
Invitrogen™ mitochondrial antibodies can be used to study the role of mitochondria in various cellular pathways and diseases. New antibodies are available for the specific detection of mitochondrial proteins including GAPDH
, and SOD2
. These antibodies are validated for multiple applications including western blots, immunocytochemistry, immunohistochemistry, immunoprecipitation, and ELISA.
Search for Primary Antibodies
CellLight® reagents are fluorescent protein–signal peptide fusions that permit specific labeling of cellular structures, including lysosomes, for live-cell imaging or for analyses following formaldehyde-based fixation. CellLight® reagents are powered by BacMam technology
, which uses a modified insect cell baculovirus coupled with a mammalian promoter to efficiently deliver and express genes in mammalian cells.
Learn More about CellLight® Reagents
Imaging lysosomes (green)
and mitochondria (red) with
Click-iT® Protein Enrichment Kit
The Click-iT® Protein Enrichment Kit
allows proteins that have metabolically or enzymatically incorporated azide-containing sugars, fatty acids, or amino acids to be efficiently captured on a resin of alkyne agarose. Bound protein is removed by standard proteolytic release upstream of protein sequencing. Superior to biotin- or lectin-based approaches, the kit is ideal for LC MS/MS–based biomarker discovery, posttranslational modification analysis, and other proteomics applications.
Learn More about Click-iT® Detection of Protein Synthesis & Posttranslational Modification
Comparison of Click-iT®
protein enrichment technology
and biotin-streptavidin protocols.
(click to enlarge)
PrestoBlue™ Cell Viability Reagent
The PrestoBlue™ Cell Viability Reagent
is a simple add-and-read cell viability assay. Once a plate containing cells and compounds is prepared, the PrestoBlue™ reagent is added and results can be read in as little as 10 minutes. The PrestoBlue™ reagent allows for reliable, high-quality cell viability data and continuous live-cell monitoring and assessment after measuring viability.
Learn More about the PrestoBlue™ Cell Viability Reagent.
Measure cell viability
in a fraction of the time
resazurin-based assays take, without loss of sensitivity.
Influenza Neuraminidase Assay Kits
Both the Applied Biosystems® NA-XTD™ Influenza Neuraminidase Assay Kit
and NA-Fluor™ Influenza Neuraminidase Assay Kit
provide chemiluminescent or fluorescent detection reagents for quantitating the sensitivity of influenza virus isolates to neuraminidase inhibitors. The NA-XTD™ assay provides longer-lasting light emission compared to the first-generation NA-Star® assay, enabling flexibility in read time and improved ease of use. The NA-Fluor™ kit provides the classic MUNANA-based assay in an easy-to-use kit format. These assays enable viral quantitation, viral growth assays, and identification of new inhibitors in cells or virus isolates.
Learn More about the NA-XTD™ Influenza Neuraminidase Assay Kit
and the NA-Fluor™ Influenza Neuraminidase Assay Kit
Neuraminidase sensitivity determination with NA-Fluor™, NA-XTD™, and NA-Star® assays.
Qubit® 2.0 Fluorometer: The Next Generation of Nucleic Acid and Protein Quantitation
Designed in response to customer feedback, the new Qubit® 2.0 Fluorometer
features an improved user interface that makes the instrument more intuitive and easier to use, while providing the same high accuracy and sensitivity as the original Qubit® Fluorometer. The new features include a larger LCD touch screen, step-by-step workflow navigation, and a USB port and automated data logging for efficient data management. See The Qubit® 2.0 Fluorometer
article, in this issue.
Learn More about the Qubit® 2.0 Fluorometer
The Qubit® 2.0 Fluorometer.
New Antibodies for Hyperosmotic Stress Research
FAK phosphorylation at tyrosine 861 has been indicated as a requirement for mammalian cells to survive under hyperosmotic stress. EGFR is also activated in downstream hyperosmotic stress signaling cascades. Invitrogen now offers two new ABfinity™ recombinant rabbit monoclonal antibodies to help elucidate FAK [pY861]
signaling. These antibodies are validated for western blotting and immunofluorescence applications.
Search for Primary Antibodies
For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.