Protein A Agarose is prepared by covalently coupling purified Protein A to 4% crosslinked agarose beads by a cyanogen bromide method. Protein A Agarose can bind >18 mg of human IgG per mL of gel, a value comparable to that reported by Hjelm et. al (1).
Protein A Agarose binds specifically to the Fc region of IgG molecules. As a result of this property, Protein A Agarose has been used to accomplish the following:
Protein A Agarose is supplied as a suspension in buffer containing 0.02 M sodium phosphate, (pH 7.2), 0.15 M sodium chloride, 0.02% (w/v) merthiolate.
For research use only. Not intended for any animal or human therapeutic or diagnostic use.
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