One resource for all your genome editing support needs. Navigate through the support categories below to obtain relevant technical information, view tips & tricks when starting an experiment, and find answers to everyday problems.


Browse our technical support and useful resources on CRISPR-Cas systems as a powerful tool for genome editing. Get tips about the engineering workflow or help with precise gene sequence targeting.

Discover the benefits of synthetic gene synthesis over traditional methods. Find troubleshooting tips and guidance for the creation of gene variants and mutations.

Find technical support content on TALEN-based genome editing. Get tips and help with targeting any locus in the genome using custom DNA binding proteins for precise genome editing.

View our tips and troubleshooting suggestions as well as useful technical resources related to GeneArt™ Engineered Cell Models, which are the world’s largest collection of engineered isogenic cell lines, including ready-to-go CRISPR-engineered cell lines.

Need assistance with CRISPR gRNA design?

Our new CRISPR Search & Design tool allows you to search our database of >600,000 predesigned CRISPR gRNAs in human and mouse genes or analyze your sequence of interest for de novo gRNA designs using our proprietary algorithms. Up to 25 gRNA sequences per gene are provided with recommendations based on potential off-target effects for each CRISPR sequence.

Start designing today

Looking for support on Cloning? Visit our Cloning Support Center.

Looking for support on DNA Isolation? Visit our Nucleic Acid Purification and Analysis Support Center.

For Research Use Only. Not for use in diagnostic procedures.