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Nipa2 encodes a protein that acts as a selective Mg(2+) transporter. The Nipa2 gene encodes a possible magnesium transporter, and is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15. Alternate splicing of the Nipa2 gene results in multiple transcript variants. Pseudogenes of the Nipa2 gene are found on chromosomes 3, 7 and 21. Diseases associated with NIPA2 include Angelman Syndrome and Prader-Willi Syndrome.
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