DNase I Antibodies

Antibodies that detect DNase I can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunoprecipitation and Immunocytochemistry. These antibodies target DNase I in Human, Bovine, Mouse, Rat and Non-human primate samples. Our DNase I... Antibodies that detect DNase I can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunoprecipitation and Immunocytochemistry. These antibodies target DNase I in Human, Bovine, Mouse, Rat and Non-human primate samples. Our DNase I polyclonal and recombinant monoclonal... Antibodies that detect DNase I can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunoprecipitation and Immunocytochemistry. These antibodies target DNase I in Human, Bovine, Mouse, Rat and Non-human primate samples. Our DNase I polyclonal and recombinant monoclonal antibodies are developed in Rabbit. Find the DNase I antibody that fits your needs. Choose from 1 of 13 DNase I antibodies, which have been validated in experiments with 3 publications and 21 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody... Antibodies that detect DNase I can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunoprecipitation and Immunocytochemistry. These antibodies target DNase I in Human, Bovine, Mouse, Rat and Non-human primate samples. Our DNase I polyclonal and recombinant monoclonal antibodies are developed in Rabbit. Find the DNase I antibody that fits your needs. Choose from 1 of 13 DNase I antibodies, which have been validated in experiments with 3 publications and 21 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Internucleosomal DNA fragmentation following the activation of endonucleases is the common end point of apoptosis. DNase I, a Ca2+/Mg2+-dependent endonuclease ubiquitously expressed in mammalian tissues, has been implicated to mediate internucleosomal DNA degradation in human cells undergoing apoptosis. DNase I is highly polymorphic, and at least six alleles of DNase I are known. DNase II, the ubiquitously expressed acidic deoxyribonuclease, acts downstream of caspase activation and may also induce DNA digestion during apoptosis. DNase I cleaves DNA to 5'-phosphodinucleotide and 5'-phospho- oligonucleotide end-products, whereas DNase II cleaves DNA to 3'-phosphomononucleotide and 3'-phosphooligonucleotide end-products. The mechanism by which DNase II cuts DNA is similar to DNase I, which produces nicks rather than double-strand cuts. DNase II is usually present in cytoplasm of epithelial cells, but it appears concentrated in the nuclei of lens fibers. In contrast, DNase I is always concentrated in nuclei of epithelial and fiber cells.

Synonyms

AI788650; deoxyribonuclease; Deoxyribonuclease 1; deoxyribonuclease I; Deoxyribonuclease1; Deoxyribonuclease-1; DeoxyribonucleaseI; DNASE 1; DNase I; DNase I lysosomal; DNase I, lysosomal; Dnase1; DNaseI; DNL 1; DNL1; Dornase alfa; DRNI; epithelial lens deoxyribonuclease I; FLJ38093; human urine deoxyribonuclease I; pancreatic deoxyribonuclease I

DNase I Antibodies

Target Information

Synonyms

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