A primary antibody is an immunoglobulin that specifically binds to a particular protein or other biomolecule of research interest for the purpose of purifying or detecting and measuring it. Primary antibodies are developed as polyclonal or monoclonal antibodies using mouse, rat, rabbit, goat, and other animal species as hosts. They are produced and supplied in various forms, ranging from crude antiserum to antigen-purified preparations. Primary antibodies for frequently researched targets are also available conjugated to fluorescent dyes or biotin.
Featured primary antibodies categories
Learn about our thousands of mouse, rat, hamster, rabbit, and other species of monoclonal primary antibodies.
Learn about our Invitrogen™ ABfinity™ rabbit monoclonal antibodies, developed by immunizing animals, screening for functionality, and then cloning the genes into high-level mammalian expression vectors.
Discover and select primary antibodies that are directly labeled or conjugated with biotin affinity tags, fluorescent dyes (Invitrogen™ Alexa Fluor™ dyes), or reporter enzymes (HRP, AP).
Find and select primary antibodies for key markers and targets relevant to cancer research, stem cell research, neurobiology research, epigenetic studies, and more.
View menus and lists of primary antibodies specific to proteins of key signaling pathways, transcription pathways, and various phosphorylation or activation states.
Find information on primary antibodies specific to fluorescent proteins, fluorescent dyes, fusion and reporter proteins, biotin, and epitope tags such as GST, His, HA, and Myc.
Select a cell marker, organelle marker, or subcellular component antibody to identify and outline cellular structures and organelles by detecting proteins that are specific to them.
Invitrogen eBioscience Super Bright polymer dyes join the Alexa Fluor dye and eFluor dye antibody conjugate portfolios to help answer complex cell biology questions—in less time and with less sample than other approaches.
This video demonstrates the dual labeling of a primary antibody. Watch how to create a fluorescent antibody-drug conjugate and learn about its application, beyond the basic function as protein detection.
For Research Use Only. Not for use in diagnostic procedures.