Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; DOC-1; downregulated in ovarian cancer 1-like; filamin A interacting protein 1-like; Filamin A-interacting protein 1-like; GIP130a; GIP130b; GIP130c; Protein down-regulated in ovarian cancer 1; protein down-regulated in ovarian cancer 1 homolog
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