An H6N1 influenza virus was isolated from a green-winged teal during the H5N1 outbreak in Hong Kong Special Administrative Region (SAR) in 1997. This virus possesses similar genes encoding internal proteins as in the human H5N1 and H9N2 influenza viruses. In 1999, influenza viruses from quail infected two humans in Hong Kong. suggesting the potential for avian influenza viruses to cross the species barrier and infect humans without prior reassortment in an intermediate host, such as the pig. The common features shared by H5N1 and H9N2 influenza viruses isolated from humans are the genes encoding the proteins of the replicating complex, the matrix protein (M) gene, the nonstructural protein (NS) gene, N1 neuraminidase (NA), This virus essentially represents the reemergence of the H5N1 influenza viruses with a different hemagglutinin (HA).
H6N1 Major Protein 1; H6N1 MP1; Influenza H6N1