Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane.
KCNK13; Potassium channel subfamily K member 13; potassium channel, subfamily K, member 13; prdx1; Tandem pore domain halothane-inhibited potassium channel 1; tandem pore domain potassium channel THIK-1; THIK-1