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Methionine-tRNA ligase (EC 6.1.1.10) catalyzes the chemical reaction: ATP + L-methionine + tRNAMet <--> AMP + diphosphate + L-methionyl-tRNAMetThe 3 substrates of this enzyme are ATP, L-methionine, and tRNA(Met), whereas its 3 products are AMP, diphosphate, and L-methionyl-tRNA(Met).This enzyme participates in 3 metabolic pathways: methionine metabolism, selenoamino acid metabolism, and aminoacyl-trna biosynthesis.
C730026E21Rik; COXPD25; EC 6.1.1.10; MARS2; methionine tRNA ligase 2, mitochondrial; methionine--tRNA ligase 2; methionine--tRNA ligase, mitochondrial; methionine-tRNA synthetase 2 (mitochondrial); methionine-tRNA synthetase 2, mitochondrial; methionyl-tRNA synthetase 2; methionyl-tRNA synthetase 2, mitochondrial; methionyl-tRNA synthetase, mitochondrial; MetRS; mitochondrial methionine--tRNA ligase; mitochondrial methionyl-tRNA synthetase; mtMetRS; RGD1311527
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