CLCF1 belongs to the interleukin-6 (IL6; MIM 147620) family of cytokines, which are involved in cell signaling through phosphorylation of gp130 (IL6ST; MIM 600694). IL6 family members share similarity in gene structure and have a 4-helix bundle in their protein structure.
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B-cell stimulating factor 3; B-cell stimulatory factor 3; B-cell-stimulating factor 3; BSF-3; BSF3; Cardiotrophin-like cytokine factor 1; CISS2; CRLF1 associated cytokine-like factor 1; neurotrophin-1/B-cell stimulating factor-3; NNT-1; NNT1; Novel neurotrophin-1