NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
NgR; NgR1; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo-66 Receptor; Nogo66 receptor; Nogo66 receptor-1; Reticulon 4 Receptor; Reticulon-4 receptor; RTN4R; UNQ330/PRO526