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This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene.
2410174K12Rik; 40-6-3; Aa1114; LOC101122608; MGC137150 protein; Protein 40-6-3; Protein SGT1 homolog; putative 40-6-3 protein; Sgt1; SGT1 homolog, MIS12 kinetochore complex assembly cochaperone; SGT1, suppressor of G2 allele of SKP1; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae); SGT1B protein; SUGT1; suppressor of G2 allele of SKP1; suppressor of G2 allele of SKP1 homolog; suppressor of G2 allele of SKP1, S. cerevisiae, homolog of; suppressor of g2 allele of SKP1-like protein
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