Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
AA420380; anti-apoptotic protein Boo; Anti-apoptotic protein NrH; apoptosis regulator Bcl-B; AU023065; Bcl-2 homolog Diva; BCL2 like 10; BCL2L10; bcl2-L-10; Bcl2-like 10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCLB; BCL-B; Boo; C85687; death inducer binding to vBcl-2 and Apaf-1; Diva
100 µL
100 µL
100 µL
100 µg
100 µL
100 µL
100 µg
100 µL
50 µg
100 µg
100 µL
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk to a specialist nowIf an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support