Bora Antibodies

Antibodies that detect Bora can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target Bora in Human, Mouse and Rat samples. Our Bora polyclonal, recombinant monoclonal,... Antibodies that detect Bora can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target Bora in Human, Mouse and Rat samples. Our Bora polyclonal, recombinant monoclonal, monoclonal and recombinant... Antibodies that detect Bora can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target Bora in Human, Mouse and Rat samples. Our Bora polyclonal, recombinant monoclonal, monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. Find the Bora antibody that fits your needs. Choose from 1 of 18 Bora antibodies, which have been validated in experiments with 1 publication and 27 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to... Antibodies that detect Bora can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target Bora in Human, Mouse and Rat samples. Our Bora polyclonal, recombinant monoclonal, monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse and Goat. Find the Bora antibody that fits your needs. Choose from 1 of 18 Bora antibodies, which have been validated in experiments with 1 publication and 27 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Bora (Protein aurora borealis) is a key activator of Aurora Related Protein Kinase A (ARK-1), which is a centrosome-associated serine/threonine kinase that regulates centrosome maturation, bipolar spindle assembly and chromosome segregation during mitosis. Bora is localized to the nucleus until mitosis is initiated, then translocates to the cytoplasm in a Cdc2 dependent manner. Activation of Cdc2 initiates the release of Bora into the cytoplasm where it can bind and activate ARK-1. PLK1 (polo-like kinase-1) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation by ARK-1. Bora and ARK-1 cooperatively activate PLK1 and control mitotic entry. Bora mutants result in multipolar spindles in mitosis identical to those observed when ARK-1 function is blocked. Thus, the ARK1-Bora-PLK1 regulatory circuit in mammalian cells elucidates a key mechanism in cell cycle regulation. At least three isoforms of Bora are known to exist.

Synonyms

6720463M24Rik; AI317232; aurora borealis; BORA; bora, aurora kinase A activator; C13orf34; HsBora; Protein aurora borealis; RGD1309522; RP11-342J4.2

Bora Antibodies

Target Information

Synonyms

Custom Antibody Service

Performance Guarantee

We're here to help

Your items have has been added!