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C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
1700025D04Rik; C10H15orf23; C15orf23; D2Ertd750e; HSD11; Kinastrin; kinetochore localized astrin (SPAG5) binding protein; kinetochore localized astrin/SPAG5 binding protein; kinetochore-localized astrin/SPAG5 binding; kinetochore-localized astrin/SPAG5 binding protein; kinetochore-localized astrin/SPAG5-binding protein; kinetochore-localized astrin-binding protein; Knstrn; putative TRAF4-associated factor 1; SKAP; small kinetochore associated protein; small kinetochore-associated protein; small kinetochore-associated protein, kinetochore-localized astrin-binding protein, TRAF4 associated factor 1; TRAF4 associated factor 1; TRAF4 associated factor 1 homolog; TRAF4AF1; TRAF4-associated factor 1; Unknown (protein for MGC:134039)
100 µL
150 µL
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