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Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.
ATP:D-hexose 6-phosphotransferase; hexokinase 3; hexokinase 3 (white cell); hexokinase iii; hexokinase type III; Hexokinase3; Hexokinase-3; Hexokinase-C; HK III; HK3; HKIII; HK-III; HXK3; RNU73859
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