Antibodies that detect HVCN1 can be used in several scientific applications, including Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target HVCN1 in Human, Rat and Mouse samples. Our HVCN1 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression to confirm specificity to HVCN1. Find the HVCN1 antibody that fits your needs. Choose from 1 of 7 HVCN1 antibodies, which have been validated in experiments with 2 publications and 28 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.
HV1; Hydrogen voltage-gated channel 1; mVSOP; Voltage sensor domain-only protein; Voltage-gated hydrogen channel 1
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