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LBX1 is the transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.
EMBL:BAE92722.1}; homeobox; HPX6; HPX-6; lady bird-like homeobox; lady bird-like homeobox 1 homolog; ladybird homeobox 1; ladybird homeobox homolog 1; ladybird homeobox homolog 1 (Drosophila); ladybird homeobox protein homolog 1; Lbx1; lbx1 {ECO:0000312; Lbx1h; LOW QUALITY PROTEIN: transcription factor LBX1; RGD1564197; Transcription factor LBX1; transcription factor similar to D. melanogaster homeodomain protein lady bird late
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