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This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.
1110068E11Rik; AU042856; homolog of yeast MAF1; MAF1; MAF1 homolog (S. cerevisiae); MAF1 homolog, negative regulator of RNA polymerase III; MAF1 negative regulator of RNA polymerase III; repressor of RNA polymerase III transcription MAF1 homolog
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