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MGARP plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. It participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. It also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.
C4orf49; CESP1; CESP-1; Corneal endothelium-specific protein 1; GS3582; HUMMR; hypoxia up-regulated mitochondrial movement regulator protein; MGARP; mitochondria localized glutamic acid rich protein; mitochondria-localized glutamic acid-rich protein; OSAP; ovary-specific acidic protein; Protein MGARP
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100 µg
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150 µL
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