This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase B (MsrB) family, and it is expressed in a variety of adult and fetal tissues.
methionine sulfoxide red. domain; methionine sulfoxide reductase b; Methionine-R-sulfoxide reductase B1; MGC3344; MsrB1; Selenoprotein R; Selenoprotein X; selenoprotein X 1; selenoprotein X, 1; SelR; SelX
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