RLTPR Antibodies

Antibodies that detect RLTPR can be used in several scientific applications, including Immunoprecipitation, Western Blot, Flow Cytometry, ELISA and Immunohistochemistry. These antibodies target RLTPR in Human and Mouse samples. Our RLTPR polyclonal and monoclonal... Antibodies that detect RLTPR can be used in several scientific applications, including Immunoprecipitation, Western Blot, Flow Cytometry, ELISA and Immunohistochemistry. These antibodies target RLTPR in Human and Mouse samples. Our RLTPR polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the... Antibodies that detect RLTPR can be used in several scientific applications, including Immunoprecipitation, Western Blot, Flow Cytometry, ELISA and Immunohistochemistry. These antibodies target RLTPR in Human and Mouse samples. Our RLTPR polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the RLTPR antibody that fits your needs. Choose from 1 of 8 RLTPR antibodies, which have been validated in experiments with 8 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for,... Antibodies that detect RLTPR can be used in several scientific applications, including Immunoprecipitation, Western Blot, Flow Cytometry, ELISA and Immunohistochemistry. These antibodies target RLTPR in Human and Mouse samples. Our RLTPR polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the RLTPR antibody that fits your needs. Choose from 1 of 8 RLTPR antibodies, which have been validated in experiments with 8 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

RLTPR/CARMIL2 (RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; capping protein regulator and myosin 1 linker 2), also known as LRRC16C, is a cytosolic protein, which with high affinity binds CAPZA2 (capping protein muscle actin Z-line alpha 2) and decreases CAPZA2 affinity for actin barbed ends. RLTPR/CARMIL2 increases the rate of actin filament elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Its interaction with CAPZA2 is essential for lamellipodial protrusion and cell translocation. RLTPR/CARMIL2 is crucial for T cell costimulation via CD28 and this property seems to be independent on its actin-uncapping function. The lack of functional RLTPR/CARMIL2 molecules impeded the differentiation toward Th1 and Th17 fates of both human and murine CD4+ T cells and leads to combined immunodeficiency. Expression of RLTPR/CARMIL2 was also detected in human and murine B cells, but it seems not to be involved in BCR-mediated signaling.

Synonyms

Capping protein regulator and myosin 1 linker 2; capping protein, Arp2/3 and myosin-I linker protein 2; CARMIL2; CARMIL2b; CG1399-PB; D130029J02Rik; F-actin-uncapping protein RLTPR; Gm585; leucine rich repeat containing 16C; leucine-rich repeat-containing protein 16C; LRRC16C; RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; RGD, leucine-rich repeat, tropomodulin and proline-rich containing protein; RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein; RLTPR

RLTPR Antibodies

Target Information

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