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SSU72 is a highly conserved homologue of yeast Ssu72, a CTD phosphatase and a component of the polyadenylation/ termination machinery. The human Ssu72 is located on Chromosome 1p36 and seems to represent a single gene. It was identified as a pRb binding factor and was also shown to interact with TFIIB and yeast PTA1. The ABs recognize a single band of approximately 30 Kda on immunoblots of various human cell lines but do not work well on mouse tissues.
1190002E22Rik; 1500011L16Rik; 2610101M12Rik; CTD phosphatase SSU72; FLJ13048; HSPC182; PNAS-120; RGD1307854; RNA polymerase II subunit A C-terminal domain phosphatase SSU72; RP5-832C2.2; SSU72; SSU72 homolog, RNA polymerase II CTD phosphatase; SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae); Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)
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