UGT1A5 Antibodies

Target Information

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.

Synonyms

B5; GNT1; UDP glucuronosyltransferase 1 family, polypeptide A5; UDP glucuronosyltransferase family 1 member A5; UDP glycosyltransferase 1 family, polypeptide A5; UDP-glucuronosyltransferase 1 family polypeptide A5s; UDP-glucuronosyltransferase 1-5; UDP-glucuronosyltransferase 1A5; UDP-glucuronosyltransferase 1-E; UDPGT; UDPGT 1-5; Ugt1; UGT1*5; UGT1.5; UGT1-05; UGT1A5; Ugt1a6; UGT1E; UGT-1E