XPNPEP3 Antibodies

Antibodies that detect XPNPEP3 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target XPNPEP3 in Human, Rat, Mouse, Canine and Non-human primate samples. Our... Antibodies that detect XPNPEP3 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target XPNPEP3 in Human, Rat, Mouse, Canine and Non-human primate samples. Our XPNPEP3 monoclonal and polyclonal... Antibodies that detect XPNPEP3 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target XPNPEP3 in Human, Rat, Mouse, Canine and Non-human primate samples. Our XPNPEP3 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Relative expression to confirm specificity to XPNPEP3. Find the XPNPEP3 antibody that fits your needs. Choose from 1 of 13 XPNPEP3 antibodies, which have been validated in experiments with 69 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced... Antibodies that detect XPNPEP3 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target XPNPEP3 in Human, Rat, Mouse, Canine and Non-human primate samples. Our XPNPEP3 monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Relative expression to confirm specificity to XPNPEP3. Find the XPNPEP3 antibody that fits your needs. Choose from 1 of 13 XPNPEP3 antibodies, which have been validated in experiments with 69 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

XPNPEP3, also known as X-Prolyl Aminopeptidase 3, is a gene located on chromosome 22q that encodes an enzyme involved in the processing of mitochondrial matrix proteins. The enzyme is classified under the M24B subfamily of metallopeptidases, which specifically remove the N-terminal amino acid from oligopeptides where the penultimate residue is proline. XPNPEP3 is implicated in conditions such as cystic kidney disease and participates in TNF-TNFR2 cellular signaling pathways. Its yeast and plant homologs, like Icp55, perform similar functions by stabilizing proteins after import into the mitochondrial matrix. Mutations in XPNPEP3 are associated with defects in ciliary structure and function, contributing to the phenotypic spectrum seen in nephronophthisis-related ciliopathies (NPHP-RCs). The crystal structure of XPNPEP3 has been resolved at 1.65 A resolution, revealing its interaction with inhibitors such as apstatin. Furthermore, XPNPEP3 is identified as a transcriptional target of the canonical Wnt/beta-catenin signaling pathway, with elevated transcript levels observed in tumors exhibiting activated Wnt signaling.

Synonyms

Aminopeptidase P3; APP3; E430012M05Rik; ICP55; Intermediate Cleaving Peptidase 55; LOW QUALITY PROTEIN: xaa-Pro aminopeptidase 3; NPHPL1; probable Xaa-Pro aminopeptidase 3; putative Xaa-Pro aminopeptidase 3; Xaa-Pro aminopeptidase 3; xaa-Pro aminopeptidase 3; probable Xaa-Pro aminopeptidase 3; XPNPEP3; X-Pro aminopeptidase 3; X-prolyl aminopeptidase (aminopeptidase P) 3, putative; X-prolyl aminopeptidase 3; X-prolyl aminopeptidase 3, mitochondrial; zgc:76905; zgc:76905 protein

XPNPEP3 Antibodies

Target Information

Synonyms

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