Anti-ZO-3 Antibodies

ZO-3 Antibodies

Antibodies that detect ZO-3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunoprecipitation, ELISA and Immunohistochemistry. These antibodies target ZO-3 in Human, Rat, Mouse and Canine samples. Our ZO-3 polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit. These antibodies have been verified by Relative Expression to confirm specificity to ZO-3. Find the ZO-3 antibody that fits your needs. Choose from 1 of 8 ZO-3 antibodies, which have been validated in experiments with 39 publications and 47 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ... View more Antibodies that detect ZO-3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunoprecipitation, ELISA and Immunohistochemistry. These antibodies target ZO-3 in Human, Rat, Mouse and Canine samples. Our ZO-3 polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit. These antibodies have been verified by Relative Expression to confirm specificity to ZO-3. Find the ZO-3 antibody that fits your needs. Choose from 1 of 8 ZO-3 antibodies, which have been validated in experiments with 39 publications and 47 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

ZO-3 is a member of the membrane associated guanylate kinse (MAGUK) family and are considered tight junction-associated proteins. Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells. ZO-3 is believed to have both structural and signaling roles, and is characteristically defined by three protein-protein interaction modules: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue.

Synonyms

tight junction protein 3; tight junction protein 3 (zona occludens 3); tight junction protein ZO-3; TJP3; TJP-3; ZO3; ZO-3; Zona occludens protein 3; zonula occludens protein 3

ZO-3 Antibodies

Target Information

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