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Proteintech
ARP2 Polyclonal Antibody
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Product Details
10922-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARP2 Fusion Protein Ag1359 (1-394 aa encoded by BC014546)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDSQGRKVV VCDNGTGFVK CGYAGSNFPE HIFPALVGRP IIRSTTKVGN IEIKDLMVGD EASELRSTLE VNYPMENGIV RNWDDMKHLW DYTFGPEKLN IDTRNCKILL TEPPMNPTKN REKIVEVMFE TYQFSGVYVA IQAVLTLYAQ GLLTGVVVDS GDGVTHICPV YESFSLPHLT RRLDIAGRDI TRYLIKLLLL RGYAFNHSAD FETVRMIKEK LCYVGYNIEQ EQKLALETTV LVESYTLPDG RIIKVGGERF EAPEALFQPH LINVEGVGVA ELLFNTIQAA DIDTRSEFYK HIVLSGGSTM YPGLPSRLER ELKQLYLERV LKGDVEKLSK FKIRIEDPPR RKHMVFLGGA VLADIMKDKD NFWMTRQEYQ EKGVRVLEKL GVTVR (1-394 aa encoded by BC014546)
Target Information
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Actin-like protein 2; Actin-related protein 2; ARP2 actin related protein 2 homolog; ARP2 actin-related protein 2 homolog; one of seven subunits of the Arp2/3 protein complex; unnamed protein product
Gene Aliases: 4921510D23Rik; AA409782; ACTR2; ARP2; D6Ertd746e
UniProt ID: (Human) P61160, (Rat) Q5M7U6, (Mouse) P61161
Entrez Gene ID: (Human) 10097, (Rat) 289820, (Mouse) 66713
establishment or maintenance of cell polarity
asymmetric cell division
positive regulation of lamellipodium assembly
meiotic chromosome movement towards spindle pole
cytosolic transport
actin cytoskeleton organization
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
positive regulation of transcription from RNA polymerase II promoter
meiotic cell cycle
spindle localization
cilium morphogenesis
cellular response to interferon-gamma
positive regulation of double-strand break repair via homologous recombination
regulation of double-strand break repair via nonhomologous end joining
cilium assembly
actin filament organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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