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Proteintech

CDK5RAP3 Polyclonal Antibody

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View all (16) CDK5RAP3 antibodies

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CDK5RAP3 Polyclonal Antibody

Product Details

11007-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50
-

Immunocytochemistry (ICC/IF)

1:50-1:500
-

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CDK5RAP3 Fusion Protein Ag1474 (1-300 aa encoded by BC009957)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Amount

19.5 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEDHQHVPI DIQTSKLLDW LVDRRHCSLK WQSLVLTIRE KINAAIQDMP ESEEIAQLLS GSYIHYFHCL RILDLLKGTE ASTKNIFGRY SSQRMKDWQE IIALYEKDNT YLVELSSLLV RNVNYEIPSL KKQIAKCQQL QQEYSRKEEE CQAGAAEMRE QFYHSCKQYG ITGENVRGEL LALVKDLPSQ LAEIGAAAQQ SLGEAIDVYQ ASVGFVCESP TEQVLPMLRF VQKRGNSTVY EWRTGTEPSV VERPHLEELP EQVAEDAIDW GDFGVEAVSE GTDSGISAEA AGIDWGIFPE S (1-300 aa encoded by BC009957)

Target Information

This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: CDK5 activator-binding protein C53; CDK5 regulatory subunit associated protein IC53-2; CDK5 regulatory subunit-associated protein 3; IC53-2; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARF-binding protein; LXXLL/leucine-zipper-containing ARFbinding protein; OK/SW-cl.114; Protein HSF-27; unnamed protein product

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Gene Aliases: C53; CDK5RAP3; HSF-27; IC53; LZAP; MST016; MSTP016; OK/SW-cl.114; PP1553

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UniProt ID: (Human) Q96JB5

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Entrez Gene ID: (Human) 80279

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Function(s)
protein binding protein kinase binding cyclin binding ubiquitin-like protein ligase binding mitogen-activated protein kinase binding NF-kappaB binding MDM2/MDM4 family protein binding protein binding, bridging involved in substrate recognition for ubiquitination
Process(es)
regulation of cyclin-dependent protein serine/threonine kinase activity liver development negative regulation of protein phosphorylation mitotic G2 DNA damage checkpoint regulation of mitotic cell cycle brain development blood circulation cell proliferation regulation of phosphatase activity apoptotic nuclear changes endoplasmic reticulum unfolded protein response positive regulation of protein ubiquitination negative regulation of NF-kappaB transcription factor activity ribosome disassembly response to endoplasmic reticulum stress negative regulation of protein catabolic process negative regulation of MAP kinase activity negative regulation of protein kinase activity by regulation of protein phosphorylation mitotic G2/M transition checkpoint regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter definitive erythrocyte differentiation protein ufmylation negative regulation of protein serine/threonine kinase activity rescue of stalled ribosome positive regulation of reticulophagy positive regulation of protein localization to nucleus positive regulation of signal transduction by p53 class mediator positive regulation of proteolysis involved in cellular protein catabolic process positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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