Product References
SARS CoV-2 mRNA vaccination exposes latent HIV to Nef-specific CD8+ T-cells.
Nature communications
Stevenson EM,Terry S,Copertino D,Leyre L,Danesh A,Weiler J,Ward AR,Khadka P,McNeil E,Bernard K,Miller IG,Ellsworth GB,Johnston CD,Finkelsztein EJ,Zumbo P,Betel D,Dündar F,Duncan MC,Lapointe HR,Speckmaier S,Moran-Garcia N,Papa MP,Nicholes S,Stover CJ,Lynch RM,Caskey M,Gaebler C,Chun TW,Bosque A,Wilkin TJ,Lee GQ,Brumme ZL,Jones RB
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Fri Aug 19 00:00:00 EDT 2022
Cancer-secreted exosomal miR-1468-5p promotes tumor immune escape via the immunosuppressive reprogramming of lymphatic vessels.
Molecular therapy : the journal of the American Society of Gene Therapy
Zhou C,Wei W,Ma J,Yang Y,Liang L,Zhang Y,Wang Z,Chen X,Huang L,Wang W,Wu S
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Wed Apr 07 00:00:00 EDT 2021
Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients.
Frontiers in cell and developmental biology
Hu Y,Chen Y,Chen Z,Zhang X,Guo C,Yu Z,Xu P,Sun L,Zhou X,Gong Y,Yu Q,Shi Y
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Wed Feb 23 00:00:00 EST 2022
T cell receptor-dependent S-acylation of ZAP-70 controls activation of T cells.
The Journal of biological chemistry
Tewari R,Shayahati B,Fan Y,Akimzhanov AM
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen.
PloS one
Liu H,Hu PW,Dubrulle J,Stossi F,Nikolai BC,Mancini MA,Rice AP
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Tue Sep 14 00:00:00 EDT 2021
Human endoglin-CD3 bispecific T cell engager antibody induces anti-tumor effect in vivo.
Theranostics
Zhong L,Shi W,Gan L,Liu X,Huo Y,Wu P,Zhang Z,Wu T,Peng H,Huang Y,Zhao Y,Yuan Y,Deng Z,Tang H
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Wed Jul 28 00:00:00 EDT 2021
Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma.
Nature communications
Zhang S,Jiang VC,Han G,Hao D,Lian J,Liu Y,Zhang R,McIntosh J,Wang R,Dang M,Dai E,Wang Y,Santos D,Badillo M,Leeming A,Chen Z,Hartig K,Bigcal J,Zhou J,Kanagal-Shamanna R,Ok CY,Lee H,Steiner RE,Zhang J,Song X,Nair R,Ahmed S,Rodriquez A,Thirumurthi S,Jain P,Wagner-Bartak N,Hill H,Nomie K,Flowers C,Futreal A,Wang L,Wang M
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Mon May 17 00:00:00 EDT 2021
Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell Activation.
Cancers
Prat M,Salon M,Allain T,Dubreuil O,Noël G,Preisser L,Jean B,Cassard L,Lemée F,Tabah-Fish I,Pipy B,Jeannin P,Prost JF,Barret JM,Coste A
12-0699 was used in Flow cytometry/Cell sorting to demonstrate here that the murlentamab opsonization of AMHRII-expressing ovarian tumor cells, in the presence of unstimulated- or tumor-associated macrophage (TAM)-like macrophages, significantly promotes macrophage-mediated ADCC and shifts the whole microenvironment towards a pro-inflammatory and anti-tumoral status, thus triggering anti-tumor activity.
Tue Apr 13 00:00:00 EDT 2021
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer.
Oncoimmunology
Tinholt M,Stavik B,Tekpli X,Garred Ø,Borgen E,Kristensen V,Sahlberg KK,Sandset PM,Iversen N
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
Unique natural killer cell subpopulations are associated with exacerbation risk in chronic obstructive pulmonary disease.
Scientific reports
Osterburg AR,Lach L,Panos RJ,Borchers MT
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Mon Jan 27 00:00:00 EST 2020
Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members.
eLife
Gonzalo-Gil E,Rapuano PB,Ikediobi U,Leibowitz R,Mehta S,Coskun AK,Porterfield JZ,Lampkin TD,Marconi VC,Rimland D,Walker BD,Deeks S,Sutton RE
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Tue Apr 09 00:00:00 EDT 2019
Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome.
Nature communications
Yang C,Siebert JR,Burns R,Gerbec ZJ,Bonacci B,Rymaszewski A,Rau M,Riese MJ,Rao S,Carlson KS,Routes JM,Verbsky JW,Thakar MS,Malarkannan S
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Mon Sep 02 00:00:00 EDT 2019
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nature communications
Walters LC,Harlos K,Brackenridge S,Rozbesky D,Barrett JR,Jain V,Walter TS,O'Callaghan CA,Borrow P,Toebes M,Hansen SG,Sacha JB,Abdulhaqq S,Greene JM,Früh K,Marshall E,Picker LJ,Jones EY,McMichael AJ,Gillespie GM
12-0699 was used in Flow cytometry/Cell sorting to elucidate the crystal structures of human leucocyte antigen E in complex with HIV and Mycobacteria tuberculosis-derived peptides.
Tue Aug 07 00:00:00 EDT 2018
VEGFR2-specific FnCAR effectively redirects the cytotoxic activity of T cells and YT NK cells.
Oncotarget
Kulemzin SV,Gorchakov AA,Chikaev AN,Kuznetsova VV,Volkova OY,Matvienko DA,Petukhov AV,Zaritskey AY,Taranin AV
12-0699 was used in Flow cytometry/Cell sorting to study the utility of fibronectin type III domains in chimeric antigen receptors for antigen recognition.
Tue Feb 06 00:00:00 EST 2018
Glossogyne tenuifolia (Hsiang-ju) extract suppresses T cell activation by inhibiting activation of c-Jun N-terminal kinase.
Chinese medicine
Houng JY,Tai TS,Hsu SC,Hsu HF,Hwang TS,Lin CJ,Fang LW
12-0699 was used in Flow cytometry/Cell sorting to study how anti-inflammatory effects exerted by GTE are mediated via suppression of JNK phosphorylation in T cell activation.
Wed Sep 30 00:00:00 EDT 2020
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
The Journal of biological chemistry
Dimitrov V,Bouttier M,Boukhaled G,Salehi-Tabar R,Avramescu RG,Memari B,Hasaj B,Lukacs GL,Krawczyk CM,White JH
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Fri Dec 15 00:00:00 EST 2017
Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation.
Scientific reports
Albert BJ,Niu A,Ramani R,Marshall GR,Wender PA,Williams RM,Ratner L,Barnes AB,Kyei GB
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2017
Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients.
Critical care (London, England)
Manson J,Cole E,De'Ath HD,Vulliamy P,Meier U,Pennington D,Brohi K
12-0699 was used in Flow cytometry/Cell sorting to study how early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients.
Tue Jun 07 00:00:00 EDT 2016
The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes.
Science signaling
So L,Lee J,Palafox M,Mallya S,Woxland CG,Arguello M,Truitt ML,Sonenberg N,Ruggero D,Fruman DA
12-0699 was used in Flow cytometry/Cell sorting to investigate the mechanism by which rapamycin leads to selective immunosupression of lymphocytes, showing that the 4E-BP-efF4E axis promotes growth and proliferation of lymphocytes and is uniquely sensitive to rapamycin in these cells.
Tue May 31 00:00:00 EDT 2016
MAIT cells are activated during human viral infections.
Nature communications
van Wilgenburg B,Scherwitzl I,Hutchinson EC,Leng T,Kurioka A,Kulicke C,de Lara C,Cole S,Vasanawathana S,Limpitikul W,Malasit P,Young D,Denney L,Moore MD,Fabris P,Giordani MT,Oo YH,Laidlaw SM,Dustin LB,Ho LP,Thompson FM,Ramamurthy N,Mongkolsapaya J,Willberg CB,Screaton GR,Klenerman P
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Thu Jun 23 00:00:00 EDT 2016
HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells.
eLife
Reeder JE,Kwak YT,McNamara RP,Forst CV,D'Orso I
12-0699 was used in Flow cytometry/Cell sorting to investigate target genes and molecular mechanisms by which Tat modulates transcription.
Wed Oct 21 00:00:00 EDT 2015
RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.
Nature communications
Jozwik A,Habibi MS,Paras A,Zhu J,Guvenel A,Dhariwal J,Almond M,Wong EHC,Sykes A,Maybeno M,Del Rosario J,Trujillo-Torralbo MB,Mallia P,Sidney J,Peters B,Kon OM,Sette A,Johnston SL,Openshaw PJ,Chiu C
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Mon Dec 21 00:00:00 EST 2015
Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function.
Molecular cell
Guo YE,Riley KJ,Iwasaki A,Steitz JA
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Thu Apr 10 00:00:00 EDT 2014
A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy.
Science translational medicine
Bruhn S,Fang Y,Barrenäs F,Gustafsson M,Zhang H,Konstantinell A,Krönke A,Sönnichsen B,Bresnick A,Dulyaninova N,Wang H,Zhao Y,Klingelhöfer J,Ambartsumian N,Beck MK,Nestor C,Bona E,Xiang Z,Benson M
12-0699 was used in Flow cytometry/Cell sorting to demonstrate a novel strategy for the identification of diagnostic markers and therapeutic candidate genes in common diseases.
Wed Jan 08 00:00:00 EST 2014
Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950)
Ji N,Somanaboeina A,Dixit A,Kawamura K,Hayward NJ,Self C,Olson GL,Forsthuber TG
12-0699 was used in Flow cytometry/Cell sorting to investigate how blocking the HLA-DR2b allele with small molecule inhibitors may offer a promising therapeutic strategy for the treatment of multiple sclerosis.
Fri Nov 15 00:00:00 EST 2013
Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C.
Journal of viral hepatitis
Yanagisawa K,Yue S,van der Vliet HJ,Wang R,Alatrakchi N,Golden-Mason L,Schuppan D,Koziel MJ,Rosen HR,Exley MA
Published figure using CD69 monoclonal antibody (Product # 12-0699-42) in Flow Cytometry
Thu Aug 01 00:00:00 EDT 2013
Role of actin dependent nuclear deformation in regulating early gene expression.
PloS one
Gupta S,Marcel N,Sarin A,Shivashankar GV
12-0699 was used in Flow cytometry/Cell sorting to highlight the importance of specific signalling intermediates accompanied with nuclear deformation in the modulation of cellular genomic programs.
Tue Jul 23 00:00:00 EDT 2013
Alleviation of insulin resistance and liver damage by oral administration of Imm124-E is mediated by increased Tregs and associated with increased serum GLP-1 and adiponectin: results of a phase I/II clinical trial in NASH.
Journal of inflammation research
Mizrahi M,Shabat Y,Ben Ya'acov A,Lalazar G,Adar T,Wong V,Muller B,Rawlin G,Ilan Y
12-0699 was used in Flow cytometry/Cell sorting to examine the reported beneficial effects of Imm124-E for the treatment of organ damage.
Tue Jan 08 00:00:00 EST 2013
Heterogeneity of multifunctional IL-17A producing S. Typhi-specific CD8+ T cells in volunteers following Ty21a typhoid immunization.
PloS one
McArthur MA,Sztein MB
12-0699 was used in Flow cytometry/Cell sorting to investigate IL-17A responses against Salmonella enterica serovar Typhi antigens in T memory subsets.
Tue Oct 02 00:00:00 EDT 2012
Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a.
BMC immunology
DeBell KE,Simhadri VR,Mariano JL,Borrego F
12-0699 was used in Flow cytometry/Cell sorting to further define the mechanism by which CD300a acts as an inhibitor of immune cell receptor signalling, showing that CD300a is required for for inhibitory signal transmission.
Thu Apr 26 00:00:00 EDT 2012
Penicillium marneffei-stimulated dendritic cells enhance HIV-1 trans-infection and promote viral infection by activating primary CD4+ T cells.
PloS one
Qin Y,Li Y,Liu W,Tian R,Guo Q,Li S,Li H,Zhang D,Zheng Y,Wu L,Lan K,Wang J
12-0699 was used in Flow cytometry/Cell sorting to demonstrate that DC interaction with HIV-1 has been exploited by P. marneffei for viral amplification.
Mon Mar 26 00:00:00 EDT 2012
Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy.
Infection and immunity
Schierloh P,Yokobori N,Alemán M,Landoni V,Geffner L,Musella RM,Castagnino J,Baldini M,Abbate E,de la Barrera SS,Sasiain MC
12-0699 was used in Flow cytometry/Cell sorting to study how the interplay between M. tuberculosis and NK cells/APC triggering IFN-gamma may play a beneficial role in tuberculous pleurisy by helping to maintain a type 1 profile.
Thu Nov 01 00:00:00 EDT 2007