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Invitrogen
MHC Class I (H-2Kd/H-2Dd) Monoclonal Antibody (34-1-2S), Biotin, eBioscience™
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FIGURE: 1 / 13
MHC Class I (H-2Kd/H-2Dd) Antibody (13-5998-81) in Flow
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 -
Figure 1 G3BP1 knockdown in BLCA cells upregulates MHC-I and impedes immune evasion. A) The effect of mRBPs on the survival of patients with BLCA who received anti-PD-L1 antibody therapy was determined using Kaplan-Meier and Cox regression analyses. The top-hit mRBPs in terms of positive correlation with the hazard ratio are presented. The mRNA expression data were derived from the IMvigor210 cohort. B) Kap... View More
Product Details
13-5998-81
Applications
Tested Dilution
Publications
Product Specifications
Published species
Mouse
Host/Isotype
Mouse
/ IgG2a, kappa
Recommended Isotype Control
Class
Monoclonal
Type
Antibody
Clone
34-1-2S
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Wet ice
RRID
Product Specific Information
Description: The 34-1-2S monoclonal antibody reacts with the mouse MHC class I, H-2Kd and H-2Dd. This cytotoxic antibody also cross-reacts with Kb, s, r, q, p.
Applications Reported: 34-1-2S has been reported for use in flow cytometric analysis.
Applications Tested: This 34-1-2S antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
This protein is an MHC class I alloantigen, which is involved in antigen presentation to T cells expressing CD3/TCR and CD8.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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