Search
Fabgennix
14-3-3 sigma Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
SFN-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 150-220 on human 14-3-3 protein sigma / STRATIFIN / SFN protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 14-3-3 protein sigma; 14-3-3 sigma protein; 14-3-3sigma; Epithelial cell marker protein 1; HGNC:10773; SFN; Stratifin; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, sigma polypeptide
Gene Aliases: Er; HME1; Mkrn3; Mme1; SFN; YWHAS
UniProt ID: (Human) P31947, (Mouse) O70456
Entrez Gene ID: (Human) 2810, (Mouse) 55948, (Rat) 313017
negative regulation of transcription from RNA polymerase II promoter
release of cytochrome c from mitochondria
keratinocyte development
negative regulation of protein kinase activity
protein export from nucleus
signal transduction
protein localization
intrinsic apoptotic signaling pathway in response to DNA damage
regulation of epidermal cell division
negative regulation of keratinocyte proliferation
regulation of cell-cell adhesion
keratinocyte differentiation
positive regulation of cell growth
keratinization
regulation of protein localization
defense response to bacterium
skin development
keratinocyte proliferation
positive regulation of epidermal cell differentiation
positive regulation of cell adhesion
negative regulation of innate immune response
positive regulation of protein export from nucleus
cytolysis in other organism
regulation of cell cycle
establishment of skin barrier
stem cell proliferation
cAMP/PKA signal transduction
non-canonical inflammasome complex assembly
negative regulation of protein localization to plasma membrane
positive regulation of cellular protein localization
negative regulation of stem cell proliferation
regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
biological_process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support