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Proteintech
VPS28 Polyclonal Antibody
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Product Details
15478-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
VPS28 Fusion Protein Ag7784 (1-221 aa encoded by BC006485)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Amount
27 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MFHGIPATP GIGAPGNKPE LYEEVKLYKN AREREKYDNM AELFAVVKTM QALEKAYIKD CVSPSEYTAA CSRLLVQYKA AFRQVQGSEI SSIDEFCRKF RLDCPLAMER IKEDRPITIK DDKGNLNRCI ADVVSLFITV MDKLRLEIRA MDEIQPDLRE LMETMHRMSH LPPDFEGRQT VSQWLQTLSG MSASDELDDS QVRQMLFDLE SAYNAFNRFL HA (1-221 aa encoded by BC006485)
Target Information
This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Caspase-activated DNase inhibitor that interacts with ASK1; CIIA; ESCRT-I complex subunit VPS28; H-Vps28; MGC60323; vacuolar protein sorting 28 homolog; vacuolar protein sorting 28 homolog (S. cerevisiae) isoform VPS28_1; vacuolar protein sorting 28 homolog (S. cerevisiae) isoform VPS28_2; vacuolar protein sorting 28-like protein; Vacuolar protein sorting-associated protein 28 homolog; VPS28, ESCRT-I subunit; yeast class E protein Vps28p homolog
Gene Aliases: 1110014J03Rik; CIIA; D730005C08Rik; VPS28
UniProt ID: (Human) Q9UK41, (Mouse) Q9D1C8
Entrez Gene ID: (Human) 51160, (Mouse) 66914, (Rat) 300052
protein transport
macroautophagy
negative regulation of protein ubiquitination
endosome transport via multivesicular body sorting pathway
multivesicular body assembly
viral budding via host ESCRT complex
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
positive regulation of protein catabolic process
membrane fission
positive regulation of ubiquitin-dependent endocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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