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Proteintech
Cytokeratin 6B Polyclonal Antibody
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Product Details
17391-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Cytokeratin 6B Fusion Protein Ag11288 (214-564 aa encoded by BC034535)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FEQYINNLR RQLDNIVGER GRLDSELRNM QDLVEDLKNK YEDEINKRTA AENEFVTLKK DVDAAYMNKV ELQAKADTLT DEINFLRALY DAELSQMQTH ISDTSVVLSM DNNRNLDLDS IIAEVKAQYE EIAQRSRAEA ESWYQTKYEE LQITAGRHGD DLRNTKQEIA EINRMIQRLR SEIDHVKKQC ANLQAAIADA EQRGEMALKD AKNKLEGLED ALQKAKQDLA RLLKEYQELM NVKLALDVEI ATYRKLLEGE ECRLNGEGVG QVNISVVQST VSSGYGGASG VGSGLGLGGG SSYSYGSGLG VGGGFSSSSG RATGGGLSSV GGGSSTIKYT TTSSSSRKSY KH (214-564 aa encoded by BC034535)
Target Information
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CK-6B; cytokeratin 6B; Cytokeratin-6B; K6B; keratin 6B, type II; keratin complex 2, basic, gene 6b; keratin, epidermal, type II, K6B; Keratin, type II cytoskeletal 6B; keratin-6-beta; Keratin-6B; keratin-like 1 (a type II keratin sequence); mK6-beta; Type-II keratin Kb10; unnamed protein product
Gene Aliases: BB144589; CK-6B; CK6B; K6B; Krt2-6b; KRT6B; KRTL1; mK6[b]; PC2; PC4
UniProt ID: (Human) P04259
Entrez Gene ID: (Human) 3854, (Mouse) 16688
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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