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Proteintech
USP21 Polyclonal Antibody
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Product Details
17856-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
USP21 Fusion Protein Ag12316 (216-565 aa encoded by BC090946)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Amount
58.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NLGNTCFLN AVLQCLSSTR PLRDFCLRRD FRQEVPGGGR AQELTEAFAD VIGALWHPDS CEAVNPTRFR AVFQKYVPSF SGYSQQDAQE FLKLLMERLH LEINRRGRRA PPILANGPVP SPPRRGGALL EEPELSDDDR ANLMWKRYLE REDSKIVDLF VGQLKSCLKC QACGYRSTTF EVFCDLSLPI PKKGFAGGKV SLRDCFNLFT KEEELESENA PVCDRCRQKT RSTKKLTVQR FPRILVLHLN RFSASRGSIK KSSVGVDFPL QRLSLGDFAS DKAGSPVYQL YALCNHSGSV HYGHYTALCR CQTGWHVYND SRVSPVSENQ VASSEGYVLF YQLMQEPPRC L (216-565 aa encoded by BC090946)
Target Information
This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Deubiquitinating enzyme 21; NEDD8-specific protease; Ubiquitin carboxyl-terminal hydrolase 21; ubiquitin specific protease 21; ubiquitin specific protease 23; Ubiquitin thioesterase 21; ubiquitin thiolesterase 21; ubiquitin-specific processing protease 21; ubiquitin-specific protease 16; Ubiquitin-specific-processing protease 21; UBP; unnamed protein product
Gene Aliases: ESTM28; PP1490; USP16; USP21; USP23; W53272
UniProt ID: (Human) Q9UK80, (Mouse) Q9QZL6
Entrez Gene ID: (Human) 27005, (Mouse) 30941
transcription coactivator activity
thiol-dependent ubiquitin-specific protease activity
protein binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
NEDD8-specific protease activity
metal ion binding
cysteine-type endopeptidase activity
thiol-dependent ubiquitinyl hydrolase activity
cysteine protease
chromatin organization
proteolysis
protein deubiquitination
ribosome disassembly
positive regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
rescue of stalled ribosome
transcription, DNA-templated
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
chromatin modification
histone deubiquitination
neuron projection development
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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