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Proteintech
ANGPTL4 Polyclonal Antibody
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Product Details
18374-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ANGPTL4 Fusion Protein Ag13237 (1-374 aa encoded by BC023647)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Amount
43.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSGAPTAGA ALMLCAATAV LLSAQGGPVQ SKSPRFASWD EMNVLAHGLL QLGQGLREHA ERTRSQLSAL ERRLSACGSA CQGTEGSTDL PLAPESRVDP EVLHSLQTQL KAQNSRIQQL FHKVAQQQRH LEKQHLRIQH LQSQFGLLDH KHLDHEVAKP ARRKRLPEMA QPVDPAHNVS RLHRLPRDCQ ELFQVGERQS GLFEIQPQGS PPFLVNCKMT SDGGWTVIQR RHDGSVDFNR PWEAYKAGFG DPHGEFWLGL EKVHSITGDR NSRLAVQLRD WDGNAELLQF SVHLGGEDTA YSLQLTAPVA GQLGATTVPP SGLSVPFSTW DQDHDLRRDK NCAKSLSGGW WFGTCSHSNL NGQYFRSIPQ QRQKL (1-374 aa encoded by BC023647)
Target Information
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 425O18-1; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGPTL2; contains fibrinogen-like domain; Fasting-i; Fasting-induced adipose factor; fibrinogen/angiopoietin-related protein; hepatic angiopoietin-related protein; Hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PPARG angiopoietin related protein; Secreted protein Bk89; unnamed protein product
Gene Aliases: ANGPTL4; ARP4; Bk89; Farp; FIAF; HARP; HFARP; Ng27; NL2; PGAR; Pgarg; PP1158; PSEC0166; TGQTL; UNQ171; UNQ171/PRO197
UniProt ID: (Human) Q9BY76, (Mouse) Q9Z1P8
Entrez Gene ID: (Human) 51129, (Mouse) 57875
angiogenesis
response to hypoxia
lipid metabolic process
blood coagulation
negative regulation of very-low-density lipoprotein particle remodeling
negative regulation of apoptotic process
protein unfolding
negative regulation of fatty acid biosynthetic process
positive regulation of angiogenesis
positive regulation of multicellular organismal process
triglyceride homeostasis
endothelial cell apoptotic process
regulation of chylomicron remodeling
negative regulation of endothelial cell apoptotic process
cellular response to starvation
positive regulation of lipid metabolic process
negative regulation of lipoprotein lipase activity
protein homooligomerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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