Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
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Protein Aliases: down regulated in metastasis; Down-regulated in metastasis protein; NNP73; Novel nucleolar protein 73; Protein Key-1A6; Small subunit processome component 20 homolog; UTP20 small subunit (SSU) processome component; UTP20 small subunit processome component; UTP20, small subunit (SSU) processome component, homolog
Gene Aliases: 1A6/DRIM; 3830408P06Rik; AA617408; DRIM; mDRIM; mDRIN; RGD1560606; UTP20
UniProt ID: (Human) O75691