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Protocadherin Gamma (pan) Monoclonal Antibody (S159-5), Biotin
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Product Details
200-306-W68
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
S159-5
Immunogen
Anti-Protocadherin Gamma (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 808-931 of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3' RACE product; Pan-Gamma-Protocadherin-A; PCDH gamma A; PCDH-gamma-A; PCDH-gamma-A4; PCDHGA; pcdhga4; protocadherin 13; protocadherin 2; protocadherin gamma a1; protocadherin gamma A12; protocadherin gamma a2; protocadherin gamma B2; protocadherin gamma B6; protocadherin gamma b7; protocadherin gamma C-VI; protocadherin gamma c5; protocadherin gamma subfamily A, 10; protocadherin gamma subfamily A, 12; protocadherin gamma subfamily A, 3; protocadherin gamma subfamily A, 4; protocadherin gamma subfamily B, 5; protocadherin gamma subfamily B, 7; protocadherin gamma subfamily C, 3; protocadherin gamma-A1; protocadherin gamma-A10; protocadherin gamma-A11; protocadherin gamma-A12; protocadherin gamma-A2; protocadherin gamma-A3; Protocadherin gamma-A4; protocadherin gamma-A5; protocadherin gamma-A6; protocadherin gamma-A6-like; protocadherin gamma-A7; protocadherin gamma-A8; protocadherin gamma-A9; protocadherin gamma-B1; protocadherin gamma-B2; protocadherin gamma-B4; protocadherin gamma-B4-like; protocadherin gamma-B5; protocadherin gamma-B6; protocadherin gamma-B6-like; protocadherin gamma-B7; protocadherin gamma-C3; protocadherin gamma-C4; protocadherin gamma-C5
Gene Aliases: mKIAA0588; mKIAA4054; pc2c; PC43; Pcdh13; Pcdh2; Pcdhga10temp; Pcdhga3; Pcdhga4; PCDHGB4; PCDHGB5; Pcdhgb7
UniProt ID: (Mouse) Q91XY4
Entrez Gene ID: (Rat) 102552497, (Rat) 102552705, (Rat) 102552796, (Rat) 553129, (Mouse) 93709, (Rat) 498849, (Mouse) 93722, (Rat) 252897, (Mouse) 93723, (Rat) 498850, (Mouse) 93724, (Mouse) 93710, (Rat) 498846, (Mouse) 93711, (Rat) 498847, (Mouse) 93712, (Rat) 252894, (Mouse) 93713, (Rat) 291637, (Mouse) 93714, (Mouse) 93715, (Rat) 291635, (Rat) 364843, (Mouse) 93716, (Rat) 252895, (Mouse) 93717, (Mouse) 93699, (Mouse) 93700, (Mouse) 93701, (Mouse) 93702, (Rat) 680448, (Mouse) 93703, (Mouse) 93704, (Rat) 364844, (Mouse) 93706, (Rat) 116782, (Mouse) 93707, (Mouse) 93708, (Rat) 641525
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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