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Proteintech
UNC5C Polyclonal Antibody
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Product Details
20240-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to UNC5C.
Target Information
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin -like domains and 2 type I thrombospondin motifs in the extracellular region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Netrin receptor UNC5C; Protein unc-5 homolog 3; Protein unc-5 homolog C; Rostral cerebellar malformation protein; UNC-5 homolog 3; unc-5 homolog C; unc5 (C.elegans homolog) c; unc5 homolog 3; unnamed protein product
Gene Aliases: B130051O18Rik; Rcm; UNC5C; UNC5H3
UniProt ID: (Human) O95185, (Mouse) O08747, (Rat) Q761X5
Entrez Gene ID: (Human) 8633, (Mouse) 22253, (Rat) 362049
apoptotic process
signal transduction
axon guidance
brain development
regulation of cell migration
anterior/posterior axon guidance
ectopic germ cell programmed cell death
netrin-activated signaling pathway
positive regulation of apoptotic process
positive regulation of developmental process
chemorepulsion of axon
dorsal root ganglion development
positive regulation of reproductive process
regulation of neuron migration
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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