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Proteintech
Calpain 7 Polyclonal Antibody
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Product Details
26985-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Calpain 7 Fusion Protein Ag25574 (1-300 aa encoded by BC056202)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDATALERD AVQFARLAVQ RDHEGRYSEA VFYYKEAAQA LIYAEMAGSS LENIQEKITE YLERVQALHS AVQSKSADPL KSKHQLDLER AHFLVTQAFD EDEKENVEDA IELYTEAVDL CLKTSYETAD KVLQNKLKQL ARQALDRAEA LGEPLTKPVG KISSTSVKPK PPPERAHFPL GANPFLERPQ SFISPQSCDA QGQRYTAEEI EVLRTTSKIN GIEYVPFMNV DLRERFAYPM PFCDRWGKLP LSPKQKTTFS KWVRPEDLTN NPTMIYTVSS FSIKQTIVSD CSFVASLAIS A (1-300 aa encoded by BC056202)
Target Information
Calpain proteinases are defined currently as papain-like neutral proteases that are calcium activated. Calpains 1 and 2 are composed of a large subunit, which is proteolytically active, and a small subunit (also called calpain-4), or enhancer protein, that is not proteolytically active. The other calpain proteins identified to date (calpain 5, 6, 8, 9, 10, 11, 12, 13, 14, 15) are not known to require a small subunit. Domains in the large subunit include the amino terminal domain-I, the proteinase domain-II, domain-III, and the EF-hand domain-IV (domain-T in calpains 5 & 6, domain-N for calpain-7). Calpain-7 domain-N does not have the standard calpain EF hand domain for binding calcium, making it unclear whether it is calcium regulated. In place of the EF hand calcium-binding domain IV, calpain-7 has a sequence most closely resembling domain-III, with unknown function. Calpain-7 is widely distributed, found in most tissues analyzed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calpain like protease; Calpain-7; homolog of Aspergillus Nidulans PALB; PalB homolog; PalBH; unnamed protein product
Gene Aliases: AU022319; CALPAIN7; CAPN7; PALBH
UniProt ID: (Human) Q9Y6W3, (Mouse) Q9R1S8
Entrez Gene ID: (Human) 23473, (Mouse) 12339
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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