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NeoBiotechnologies
Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (LL002), Biotin
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Product Details
3861-MSM1-B1
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG3, kappa
Class
Monoclonal
Type
Antibody
Clone
LL002
Immunogen
A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
Conjugate
Form
Liquid
Concentration
100 µg/mL
Amount
50 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-14; cytokeratin 14; Cytokeratin-14; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; Keratin, type I cytoskeletal 14; Keratin-14; Koebner; Type I keratin Ka14
Gene Aliases: AI626930; CK14; EBS1; EBS1A; EBS1B; EBS1C; EBS1D; EBS3; EBS4; K14; Ka14; Krt-1.14; Krt1-14; KRT14; NFJ
UniProt ID: (Human) P02533, (Mouse) Q61781, (Rat) Q6IFV1
Entrez Gene ID: (Human) 3861, (Mouse) 16664, (Rat) 287701
morphogenesis of an epithelium
epidermis development
response to radiation
keratinocyte differentiation
hair cycle
intermediate filament organization
intermediate filament bundle assembly
stem cell differentiation
aging
epithelial cell differentiation
response to zinc ion
response to ionizing radiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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