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Invitrogen
MST3 Monoclonal Antibody (ZM003)
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FIGURE: 1 / 3
MST3 Antibody (39-6200) in ICC/IF
Immunofluorescence analysis of MST3 was performed using 70% confluent log phase SH-SY5Y cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with MST3 (ZM003) Mouse Monoclonal Antibody (Product # 39-6200) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A28... View More
Product Details
39-6200
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
ZM003
Immunogen
Synthetic peptide derived from the N-terminal region of the human MST3 protein
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
STK24 (MST3) is a serine/threonine kinase that is a member of the GCK subfamily of STE20-like proteins. The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 95; Mammalian STE20-like protein kinase 3; MST-3; OTTHUMP00000018594; protein serine/threonine kinase; RP11-111L24.5; serine/threonine kinase 24 (STE20 homolog, yeast); Serine/threonine-protein kinase 24; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK24; unnamed protein product
Gene Aliases: HEL-S-95; MST3; MST3B; STE20; STK24; STK3
UniProt ID: (Human) Q9Y6E0
Entrez Gene ID: (Human) 8428
protein phosphorylation
apoptotic process
signal transduction
intrinsic apoptotic signaling pathway in response to oxidative stress
cellular response to starvation
negative regulation of cell migration
cellular response to oxidative stress
intracellular signal transduction
protein autophosphorylation
regulation of axon regeneration
execution phase of apoptosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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